Coat: Hairless, albino background
Developed from the transfer of the nude gene from Crl:NU-Foxn1nu to a CD-1® mouse.
The development involved a series of crosses and backcrosses beginning in 1979 at Charles River Laboratories, Wilmington, MA. In 2023, Harlan Laboratories Ltd. attained independent status.
The animal lacks a thymus, rendering it unable to produce T-cells and, therefore, immunodeficient.
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