Coat: Albino
Highly susceptible to opportunistic viral and bacterial infections
Natural Killer (NK) cell, macrophage, and granulocyte cell numbers and function are normal
As SCID mice age, a variable percentage become ‘leaky’ due to the spontaneous development of functional T and B lymphocytes
Autosomal-recessive, single-nucleotide polymorphism within the Prkdc gene on chromosome 16
Severe combined immunodeficiency affecting T- and B-cell development
